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Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress

The present study aimed to analyze novel mechanisms underlying Nrf2-mediated anti-apoptosis in periodontal ligament stem cells (PDLSCs) in the periodontitis oxidative microenvironment. We created an oxidative stress model with H(2)O(2)-treated PDLSCs. We used real-time PCR, Western blotting, TUNEL s...

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Detalles Bibliográficos
Autores principales: Liu, Yanli, Yang, Hongxu, Wen, Yi, Li, Bingyi, Zhao, Yinhua, Xing, Jing, Zhang, Min, Chen, Yongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454985/
https://www.ncbi.nlm.nih.gov/pubmed/28513573
http://dx.doi.org/10.3390/ijms18051076