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Cellular Repair of DNA–DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane

Xenobiotic-induced interstrand DNA–DNA cross-links (ICL) interfere with transcription and replication and can be converted to toxic DNA double strand breaks. In this work, we investigated cellular responses to 1,4-bis-(guan-7-yl)-2,3-butanediol (bis-N7G-BD) cross-links induced by 1,2,3,4-diepoxybuta...

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Detalles Bibliográficos
Autores principales: Chesner, Lisa N., Degner, Amanda, Sangaraju, Dewakar, Yomtoubian, Shira, Wickramaratne, Susith, Malayappan, Bhaskar, Tretyakova, Natalia, Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454995/
https://www.ncbi.nlm.nih.gov/pubmed/28524082
http://dx.doi.org/10.3390/ijms18051086