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The Impact of SMAD4 Loss on Outcome in Patients with Advanced Pancreatic Cancer Treated with Systemic Chemotherapy

The role of the tumor suppressor mothers against decapentaplegic homolog 4 (SMAD4) has not yet been defined in patients (pts) with advanced pancreatic cancer (aPC). This translational research study was designed to evaluate the impact of tumoral SMAD4 loss on clinicopathological parameters and outco...

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Detalles Bibliográficos
Autores principales: Ormanns, Steffen, Haas, Michael, Remold, Anna, Kruger, Stephan, Holdenrieder, Stefan, Kirchner, Thomas, Heinemann, Volker, Boeck, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455003/
https://www.ncbi.nlm.nih.gov/pubmed/28534865
http://dx.doi.org/10.3390/ijms18051094