Simple adjustment of the sequence weight algorithm remarkably enhances PSI-BLAST performance

BACKGROUND: PSI-BLAST, an extremely popular tool for sequence similarity search, features the utilization of Position-Specific Scoring Matrix (PSSM) constructed from a multiple sequence alignment (MSA). PSSM allows the detection of more distant homologs than a general amino acid substitution matrix...

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Detalles Bibliográficos
Autores principales: Oda, Toshiyuki, Lim, Kyungtaek, Tomii, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455086/
https://www.ncbi.nlm.nih.gov/pubmed/28578660
http://dx.doi.org/10.1186/s12859-017-1686-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455086/
https://www.ncbi.nlm.nih.gov/pubmed/28578660
http://dx.doi.org/10.1186/s12859-017-1686-9

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