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Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes
BACKGROUND: Abnormal lipid metabolism may contribute to an increase in endoplasmic reticulum (ER) stress, resulting in the pathogenesis of non-alcoholic steatohepatitis. Apolipoprotein A-I (apoA-I) accepts cellular free cholesterol and phospholipids transported by ATP-binding cassette transporter A1...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455103/ https://www.ncbi.nlm.nih.gov/pubmed/28577569 http://dx.doi.org/10.1186/s12944-017-0497-3 |