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Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes

BACKGROUND: Abnormal lipid metabolism may contribute to an increase in endoplasmic reticulum (ER) stress, resulting in the pathogenesis of non-alcoholic steatohepatitis. Apolipoprotein A-I (apoA-I) accepts cellular free cholesterol and phospholipids transported by ATP-binding cassette transporter A1...

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Detalles Bibliográficos
Autores principales: Guo, Qing, Zhang, Can, Wang, Yutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455103/
https://www.ncbi.nlm.nih.gov/pubmed/28577569
http://dx.doi.org/10.1186/s12944-017-0497-3