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The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's Disease
The “therapeutic chelation” approach to treating Alzheimer's disease (AD) evolved from the metals hypothesis, with the premise that small molecules can be designed to prevent transition metal-induced amyloid deposition and oxidative stress within the AD brain. Over more than 20 years, countless...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455140/ https://www.ncbi.nlm.nih.gov/pubmed/28626387 http://dx.doi.org/10.3389/fnins.2017.00317 |