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In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway

BACKGROUND: Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the only neurotrophic factors as yet identified in invertebrates with conserved amino...

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Detalles Bibliográficos
Autores principales: Lindström, Riitta, Lindholm, Päivi, Palgi, Mari, Saarma, Mart, Heino, Tapio I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455201/
https://www.ncbi.nlm.nih.gov/pubmed/28578657
http://dx.doi.org/10.1186/s12863-017-0509-3