Cargando…

In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway

BACKGROUND: Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the only neurotrophic factors as yet identified in invertebrates with conserved amino...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindström, Riitta, Lindholm, Päivi, Palgi, Mari, Saarma, Mart, Heino, Tapio I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455201/ https://www.ncbi.nlm.nih.gov/pubmed/28578657 http://dx.doi.org/10.1186/s12863-017-0509-3

Ejemplares similares

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster
por: Lindström, Riitta, et al.
Publicado: (2016)

Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
por: Lindström, Riitta, et al.
Publicado: (2013)

Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes
por: Palgi, Mari, et al.
Publicado: (2012)

CDNF and MANF regulate ER stress in a tissue-specific manner
por: Pakarinen, Emmi, et al.
Publicado: (2022)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function
por: Danilova, Tatiana, et al.
Publicado: (2019)

MANF silencing, immunity induction or autophagy trigger an unusual cell type in metamorphosing Drosophila brain
por: Stratoulias, Vassilis, et al.
Publicado: (2014)

Neuroplastin Modulates Anti-inflammatory Effects of MANF
por: Yagi, Takuya, et al.
Publicado: (2020)

The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
por: Eesmaa, Ave, et al.
Publicado: (2021)

MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex
por: Tseng, Kuan-Yin, et al.
Publicado: (2017)

MANF protects human pancreatic beta cells against stress-induced cell death
por: Hakonen, Elina, et al.
Publicado: (2018)

CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson’s disease
por: Pakarinen, Emmi, et al.
Publicado: (2023)

Downregulation of DmMANF in Glial Cells Results in Neurodegeneration and Affects Sleep and Lifespan in Drosophila melanogaster
por: Walkowicz, Lucyna, et al.
Publicado: (2017)

Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism
por: Lindholm, Päivi, et al.
Publicado: (2021)

MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System
por: Pakarinen, Emmi, et al.
Publicado: (2020)

Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
por: Herranen, Anni, et al.
Publicado: (2020)

Characterization of Drosophila GDNF Receptor-Like and Evidence for Its Evolutionarily Conserved Interaction with Neural Cell Adhesion Molecule (NCAM)/FasII
por: Kallijärvi, Jukka, et al.
Publicado: (2012)

Poststroke delivery of MANF promotes functional recovery in rats
por: Mätlik, Kert, et al.
Publicado: (2018)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats
por: Renko, Juho-Matti, et al.
Publicado: (2018)

MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea
por: Ikäheimo, Kuu, et al.
Publicado: (2021)

Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy
por: Galli, Emilia, et al.
Publicado: (2019)

Increased Serum Levels of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Subjects With Parkinson’s Disease
por: Galli, Emilia, et al.
Publicado: (2019)

Spatiotemporal Expression of MANF in the Developing Rat Brain
por: Wang, Haiping, et al.
Publicado: (2014)

RegB Kinase Activity Is Controlled in Part by Monitoring the Ratio of Oxidized to Reduced Ubiquinones in the Ubiquinone Pool
por: Wu, Jiang, et al.
Publicado: (2010)

Reduction of Hydrophilic Ubiquinones by the Flavin in Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I) and Production of Reactive Oxygen Species
por: King, Martin S., et al.
Publicado: (2009)

A Comparative Analysis of the Molecular Features of MANF and CDNF
por: Norisada, Junpei, et al.
Publicado: (2016)

Trophic Factors in Inflammation and Regeneration: The Role of MANF and CDNF
por: Sousa-Victor, Pedro, et al.
Publicado: (2018)

Diagnostic and Prognostic Values of MANF Expression in Hepatocellular Carcinoma
por: He, Jingyi, et al.
Publicado: (2020)

UPR Responsive Genes Manf and Xbp1 in Stroke
por: Lõhelaid, Helike, et al.
Publicado: (2022)

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes
por: Galli, Emilia, et al.
Publicado: (2016)

Computational Identification and Analysis of Ubiquinone-Binding Proteins
por: Lu, Chang, et al.
Publicado: (2020)

Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless
por: Tamberg, Laura, et al.
Publicado: (2015)

Photoreceptor Protection by Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
por: Lu, Jianmin, et al.
Publicado: (2018)

MANF regulates hypothalamic control of food intake and body weight
por: Yang, Su, et al.
Publicado: (2017)

MANF: A New Player in the Control of Energy Homeostasis, and Beyond
por: Yang, Su, et al.
Publicado: (2018)

The ubiquinone synthesis pathway is a promising drug target for Chagas disease
por: Nara, Takeshi, et al.
Publicado: (2021)

Chemistry of Lipoquinones: Properties, Synthesis, and Membrane Location of Ubiquinones, Plastoquinones, and Menaquinones
por: Braasch-Turi, Margaret M., et al.
Publicado: (2022)

Commentary: Synthetic Ubiquinones Specifically Bind to Mitochondrial Voltage-Dependent Anion Channel 1 (VDAC1) in Saccharomyces cerevisiae Mitochondria
por: Gutiérrez-Aguilar, Manuel
Publicado: (2017)

Functional Analysis of Polyprenyl Diphosphate Synthase Genes Involved in Plastoquinone and Ubiquinone Biosynthesis in Salvia miltiorrhiza
por: Liu, Miaomiao, et al.
Publicado: (2019)

UbiN, a novel Rhodobacter capsulatus decarboxylative hydroxylase involved in aerobic ubiquinone biosynthesis
por: Nagatani, Haruka, et al.
Publicado: (2023)

Nonspecific resistance to bacterial infections. Enhancement by ubiquinone-8
Publicado: (1978)

Cannot write session to /tmp/vufind_sessions/sess_3tpvntd0c744sksood3vdo8f84