Suboptimal Dosing Parameters as Possible Factors in the Negative Phase III Clinical Trials of Progesterone for Traumatic Brain Injury

To date, outcomes for all Phase III clinical trials for traumatic brain injury (TBI) have been negative. The recent disappointing results of the Progesterone for the Treatment of Traumatic Brain Injury (ProTECT) and Study of a Neuroprotective Agent, Progesterone, in Severe Traumatic Brain Injury (Sy...

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Detalles Bibliográficos
Autores principales: Howard, Randy B., Sayeed, Iqbal, Stein, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455214/
https://www.ncbi.nlm.nih.gov/pubmed/26370183
http://dx.doi.org/10.1089/neu.2015.4179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455214/
https://www.ncbi.nlm.nih.gov/pubmed/26370183
http://dx.doi.org/10.1089/neu.2015.4179

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