Impact of a Panel of 88 Single Nucleotide Polymorphisms on the Risk of Breast Cancer in High-Risk Women: Results From Two Randomized Tamoxifen Prevention Trials

PURPOSE: At least 94 common single nucleotide polymorphisms (SNPs) are associated with breast cancer. The extent to which an SNP panel can refine risk in women who receive preventive therapy has not been directly assessed previously. MATERIALS AND METHODS: A risk score on the basis of 88 SNPs (SNP88...

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Detalles Bibliográficos
Autores principales: Cuzick, Jack, Brentnall, Adam R., Segal, Corrinne, Byers, Helen, Reuter, Caroline, Detre, Simone, Lopez-Knowles, Elena, Sestak, Ivana, Howell, Anthony, Powles, Trevor J., Newman, William G., Dowsett, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2017
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455424/
https://www.ncbi.nlm.nih.gov/pubmed/28029312
http://dx.doi.org/10.1200/JCO.2016.69.8944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455424/
https://www.ncbi.nlm.nih.gov/pubmed/28029312
http://dx.doi.org/10.1200/JCO.2016.69.8944

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