Trastuzumab Emtansine With or Without Pertuzumab Versus Trastuzumab Plus Taxane for Human Epidermal Growth Factor Receptor 2–Positive, Advanced Breast Cancer: Primary Results From the Phase III MARIANNE Study

PURPOSE: Trastuzumab and pertuzumab are human epidermal growth factor receptor 2 (HER2) –targeted monoclonal antibodies, and trastuzumab emtansine (T-DM1) is an antibody–drug conjugate that combines the properties of trastuzumab with the cytotoxic activity of DM1. T-DM1 demonstrated encouraging effi...

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Detalles Bibliográficos
Autores principales: Perez, Edith A., Barrios, Carlos, Eiermann, Wolfgang, Toi, Masakazu, Im, Young-Hyuck, Conte, Pierfranco, Martin, Miguel, Pienkowski, Tadeusz, Pivot, Xavier, Burris, Howard A., Petersen, Jennifer A., Stanzel, Sven, Strasak, Alexander, Patre, Monika, Ellis, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2017
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455677/
https://www.ncbi.nlm.nih.gov/pubmed/28056202
http://dx.doi.org/10.1200/JCO.2016.67.4887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455677/
https://www.ncbi.nlm.nih.gov/pubmed/28056202
http://dx.doi.org/10.1200/JCO.2016.67.4887

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