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A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition

The inability of neurites to grow and restore neural connections is common to many neurological disorders, including trauma to the central nervous system and neurodegenerative diseases. Therefore, there is need for a robust and reproducible model of neurite outgrowth, to provide a tool to study the...

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Detalles Bibliográficos
Autores principales: Clarke, Kirsty E., Tams, Daniel M., Henderson, Andrew P., Roger, Mathilde F., Whiting, Andrew, Przyborski, Stefan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455986/
https://www.ncbi.nlm.nih.gov/pubmed/28011165
http://dx.doi.org/10.1016/j.neuint.2016.12.009