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Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discovery

Valosin Containing Protein (VCP) disease is an autosomal dominant multisystem proteinopathy caused by mutations in the VCP gene, and is primarily associated with progressive muscle weakness, including atrophy of the pelvic and shoulder girdle muscles. Currently, no treatments are available and cardi...

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Detalles Bibliográficos
Autores principales: Llewellyn, Katrina J., Nalbandian, Angèle, Weiss, Lan N., Chang, Isabela, Yu, Howard, Khatib, Bibo, Tan, Baichang, Scarfone, Vanessa, Kimonis, Virginia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456028/
https://www.ncbi.nlm.nih.gov/pubmed/28575052
http://dx.doi.org/10.1371/journal.pone.0176919