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Follistatin like-1 (Fstl1) is required for the normal formation of lung airway and vascular smooth muscle at birth

Fstl1, a secreted protein of the BMP antagonist class, has been implicated in the regulation of lung development and alveolar maturation. Here we generated a Fstl1-lacZ reporter mouse line as well as a Fstl1 knockout allele. We localized Fstl1 transcript in lung smooth muscle cells and identified Fs...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Liu, Yingying, Li, Xiaohe, Zhao, Jing, Geng, Yan, Ning, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456059/
https://www.ncbi.nlm.nih.gov/pubmed/28574994
http://dx.doi.org/10.1371/journal.pone.0177899