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Follistatin like-1 (Fstl1) is required for the normal formation of lung airway and vascular smooth muscle at birth
Fstl1, a secreted protein of the BMP antagonist class, has been implicated in the regulation of lung development and alveolar maturation. Here we generated a Fstl1-lacZ reporter mouse line as well as a Fstl1 knockout allele. We localized Fstl1 transcript in lung smooth muscle cells and identified Fs...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456059/ https://www.ncbi.nlm.nih.gov/pubmed/28574994 http://dx.doi.org/10.1371/journal.pone.0177899 |