NGR-peptide−drug conjugates with dual targeting properties

Peptides containing the asparagine-glycine-arginine (NGR) motif are recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature. Spontaneous decomposition of NGR peptides can result in isoAsp derivatives, which are recognized by RGD-binding...

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Detalles Bibliográficos
Autores principales: Enyedi, Kata Nóra, Tóth, Szilárd, Szakács, Gergely, Mező, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456102/
https://www.ncbi.nlm.nih.gov/pubmed/28575020
http://dx.doi.org/10.1371/journal.pone.0178632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456102/
https://www.ncbi.nlm.nih.gov/pubmed/28575020
http://dx.doi.org/10.1371/journal.pone.0178632

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