Sustained Release of Lidocaine from Solvent-Free Biodegradable Poly[(d,l)-Lactide-co-Glycolide] (PLGA): In Vitro and In Vivo Study

Local anesthetics are commonly used for pain relief by regional nerve blocking. In this study, we fabricated solvent-free biodegradable pellets to extend the duration of lidocaine release without any significant local or systemic toxicity levels. To manufacture the pellets, poly[(d,l)-lactide-co-gly...

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Detalles Bibliográficos
Autores principales: Kau, Yi-Chuan, Liao, Chia-Chih, Chen, Ying-Chi, Liu, Shih-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456155/
https://www.ncbi.nlm.nih.gov/pubmed/28788205
http://dx.doi.org/10.3390/ma7096660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456155/
https://www.ncbi.nlm.nih.gov/pubmed/28788205
http://dx.doi.org/10.3390/ma7096660

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