Cargando…

Sustained Release of Lidocaine from Solvent-Free Biodegradable Poly[(d,l)-Lactide-co-Glycolide] (PLGA): In Vitro and In Vivo Study

Local anesthetics are commonly used for pain relief by regional nerve blocking. In this study, we fabricated solvent-free biodegradable pellets to extend the duration of lidocaine release without any significant local or systemic toxicity levels. To manufacture the pellets, poly[(d,l)-lactide-co-gly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kau, Yi-Chuan, Liao, Chia-Chih, Chen, Ying-Chi, Liu, Shih-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456155/ https://www.ncbi.nlm.nih.gov/pubmed/28788205 http://dx.doi.org/10.3390/ma7096660

Ejemplares similares

Double-Walled Poly-(D,L-lactide-co-glycolide) (PLGA) and Poly(L-lactide) (PLLA) Nanoparticles for the Sustained Release of Doxorubicin
por: Cardoso, M. Margarida, et al.
Publicado: (2021)

Controlled Release of Lysozyme from Double-Walled Poly(Lactide-Co-Glycolide) (PLGA) Microspheres
por: Ansary, Rezaul H., et al.
Publicado: (2017)

Microencapsulation of Thymol in Poly(lactide-co-glycolide) (PLGA): Physical and Antibacterial Properties
por: Zhu, Zhu, et al.
Publicado: (2019)

Imparting Superhydrophobicity to Biodegradable Poly(lactide-co-glycolide) Electrospun Meshes
por: Kaplan, Jonah A., et al.
Publicado: (2014)

Biodegradable membrane of poly(l-lactide acid-dioxanone-glycolide) and stereocomplex poly(lactide) with enhanced crystallization and biocompatibility
por: Fan, Tiantang, et al.
Publicado: (2022)

Designing Biodegradable Wafers Based on Poly(L-lactide-co-glycolide) and Poly(glycolide-co-ε-caprolactone) for the Prolonged and Local Release of Idarubicin for the Therapy of Glioblastoma Multiforme
por: Turek, Artur, et al.
Publicado: (2020)

Super-Tough and Biodegradable Poly(lactide-co-glycolide) (PLGA) Transparent Thin Films Toughened by Star-Shaped PCL-b-PDLA Plasticizers
por: Jeong, Jieun, et al.
Publicado: (2023)

Biodegradable Vancomycin-eluting Poly[(d,l)-lactide-co-glycolide] Nanofibres for the Treatment of Postoperative Central Nervous System Infection
por: Tseng, Yuan-Yun, et al.
Publicado: (2015)

Controlled Release of Octreotide and Assessment of Peptide Acylation from Poly(D,L-lactide-co-hydroxymethyl glycolide) Compared to PLGA Microspheres
por: Ghassemi, Amir H., et al.
Publicado: (2011)

Efficacy of vancomycin-releasing biodegradable poly(lactide-co-glycolide) antibiotics beads for treatment of experimental bone infection due to Staphylococcus aureus
por: Ueng, Steve W. N., et al.
Publicado: (2016)

Preparation of poly(lactide-co-glycolide) microspheres and evaluation of pharmacokinetics and tissue distribution of BDMC-PLGA-MS in rats
por: Li, Guozhuan, et al.
Publicado: (2018)

Influence of Radiation Sterilization on Properties of Biodegradable Lactide/Glycolide/Trimethylene Carbonate and Lactide/Glycolide/ε-caprolactone Porous Scaffolds with Shape Memory Behavior
por: Rychter, Piotr, et al.
Publicado: (2016)

Biodegradable Scaffolds for Vascular Regeneration Based on Electrospun Poly(L-Lactide-co-Glycolide)/Poly(Isosorbide Sebacate) Fibers
por: Śmiga-Matuszowicz, Monika, et al.
Publicado: (2023)

Potential Antibacterial Activity of Carvacrol-Loaded Poly(DL-lactide-co-glycolide) (PLGA) Nanoparticles against Microbial Biofilm
por: Iannitelli, Antonio, et al.
Publicado: (2011)

The Effect of Temozolomide/Poly(lactide-co-glycolide) (PLGA)/Nano-Hydroxyapatite Microspheres on Glioma U87 Cells Behavior
por: Zhang, Dongyong, et al.
Publicado: (2012)

The Design of Poly(lactide-co-glycolide) Nanocarriers for Medical Applications
por: Essa, Divesha, et al.
Publicado: (2020)

A Dual-sensitive Hydrogel Based on Poly(Lactide-co-Glycolide)-Polyethylene Glycol-Poly(Lactide-co-Glycolide) Block Copolymers for 3D Printing
por: Zhou, Yang, et al.
Publicado: (2021)

Harnessing Dendritic Cells for Poly (D,L-lactide-co-glycolide) Microspheres (PLGA MS)—Mediated Anti-tumor Therapy
por: Koerner, Julia, et al.
Publicado: (2019)

Encapsulation of Low Metronidazole Dose in Poly (D,L-lactide-co-glycolide) (PLGA) Nanoparticles Improves Giardia intestinalis Treatment
por: Madbouly, Neveen Adel, et al.
Publicado: (2020)

Biodegradable Poly(D-L-lactide-co-glycolide) (PLGA)-Infiltrated Bioactive Glass (CAR12N) Scaffolds Maintain Mesenchymal Stem Cell Chondrogenesis for Cartilage Tissue Engineering
por: Gögele, Clemens, et al.
Publicado: (2022)

Poly(d,l-lactide-co-glycolide) (PLGA) Nanoparticles Loaded with Proteolipid Protein (PLP)—Exploring a New Administration Route
por: Lima, Alexandre Ferreira, et al.
Publicado: (2020)

Cinnamaldehyde Loaded Poly(lactide-co-glycolide) (PLGA) Microparticles for Antifungal Delivery Application against Resistant Candida albicans and Candida glabrata
por: Rizzo, Silvia, et al.
Publicado: (2023)

Adriamycin release from poly(lactide-co-glycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization
por: Davaran, Soodabeh, et al.
Publicado: (2006)

Immobilization of poly(lactide-co-glycolide) microspheres on bone implant materials for antibiotic release and the binding mechanisms
por: Wang, Dongwei, et al.
Publicado: (2020)

Comparison of Closure of Gastric Perforation Ulcers With Biodegradable Lactide-Glycolide-Caprolactone or Omental Patches
por: Bertleff, Marietta J. O. E., et al.
Publicado: (2009)

Role of the Lactide:Glycolide Ratio in PLGA Nanoparticle Stability and Release under Lysosomal Conditions for Enzyme Replacement Therapy of Lysosomal Storage Disorders
por: del Moral, Maria, et al.
Publicado: (2023)

Poly(lactide-co-glycolide)/Hydroxyapatite Porous Scaffold with Microchannels for Bone Regeneration
por: Zhang, Ning, et al.
Publicado: (2016)

Drug delivery of 6-bromoindirubin-3’-glycerol-oxime ether employing poly(d,l-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solvents
por: Czapka, Anna, et al.
Publicado: (2022)

Suggested Procedures for the Reproducible Synthesis of Poly(d,l-lactide-co-glycolide) Nanoparticles Using the Emulsification Solvent Diffusion Platform
por: Haque, Shadabul, et al.
Publicado: (2018)

Enhanced Paclitaxel Efficacy to Suppress Triple-Negative Breast Cancer Progression Using Metronomic Chemotherapy with a Controlled Release System of Electrospun Poly-d-l-Lactide-Co-Glycolide (PLGA) Nanofibers
por: Hsu, Ming-Yi, et al.
Publicado: (2021)

Influence of Hydroxyapatite Surface Functionalization on Thermal and Biological Properties of Poly(l-Lactide)- and Poly(l-Lactide-co-Glycolide)-Based Composites
por: Gazińska, Małgorzata, et al.
Publicado: (2020)

Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres
por: Du, Liping, et al.
Publicado: (2021)

Ciprofloxacin-Releasing ROS-Sensitive Nanoparticles Composed of Poly(Ethylene Glycol)/Poly(D,L-lactide-co-glycolide) for Antibacterial Treatment
por: Song, Jaeik, et al.
Publicado: (2021)

Optimization and Designing of Amikacin-loaded Poly D, L-Lactide-co-glycolide Nanoparticles for Effective and Sustained Drug Delivery
por: Fatima, Saman, et al.
Publicado: (2019)

Enhanced antibacterial activity of roxithromycin loaded pegylated poly lactide-co-glycolide nanoparticles
por: Koopaei, Mona Noori, et al.
Publicado: (2012)

Rational Mitomycin Nanocarriers Based on Hydrophobically Functionalized Polyelectrolytes and Poly(lactide-co-glycolide)
por: Lamch, Łukasz, et al.
Publicado: (2022)

Fabrication of Ropivacaine/Dexamethasone-Eluting Poly(D, L-lactide-co-glycolide) Microparticles via Electrospraying Technique for Postoperational Pain Control
por: Shen, Shih-Jyun, et al.
Publicado: (2022)

Pleurocidin Peptide Enhances Grouper Anti-Vibrio harveyi Immunity Elicited by Poly(lactide-co-glycolide)-Encapsulated Recombinant Glyceraldehyde-3-phosphate Dehydrogenase
por: Chuang, Shu-Chun, et al.
Publicado: (2014)

Primary biocompatibility tests of poly(lactide-co-glycolide)-(poly-L-orithine/fucoidan) core–shell nanocarriers
por: Cai, Duanhua, et al.
Publicado: (2018)

Preparation and Characterization of Poly(D,L-Lactide-co-Glycolide) Nanoparticles Containing Ascorbic Acid
por: Stevanović, Magdalena M., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_kav7ggqv4ese8mjb7f3p7nnonl