Natural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts

Alzheimer’s disease is characterized by pathogenic oligomerization, aggregation, and deposition of amyloid beta peptide (Aβ), resulting in severe neuronal toxicity and associated cognitive dysfunction. In particular, increases in the absolute or relative level of the major long form of Aβ, Aβ42, are...

Descripción completa

Detalles Bibliográficos
Autores principales: Findeis, Mark A., Schroeder, Frank C., Creaser, Steffen P., McKee, Timothy D., Xia, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456218/
https://www.ncbi.nlm.nih.gov/pubmed/28930205
http://dx.doi.org/10.3390/medicines2030127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456218/
https://www.ncbi.nlm.nih.gov/pubmed/28930205
http://dx.doi.org/10.3390/medicines2030127

Ejemplares similares