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Natural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts
Alzheimer’s disease is characterized by pathogenic oligomerization, aggregation, and deposition of amyloid beta peptide (Aβ), resulting in severe neuronal toxicity and associated cognitive dysfunction. In particular, increases in the absolute or relative level of the major long form of Aβ, Aβ42, are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456218/ https://www.ncbi.nlm.nih.gov/pubmed/28930205 http://dx.doi.org/10.3390/medicines2030127 |