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Necrostatin-1 Attenuates Inflammatory Response and Improves Cognitive Function in Chronic Ischemic Stroke Mice

Multiple cell death is involved in ischemic brain injury. Necroptosis, a recently reported cell death, may be the most suitable cell death mechanism in a subpopulation of neurons under ischemic injury. It reported that a small molecule, necrostatin-1 (Nec-1), has a potent inhibitory effect on necrop...

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Detalles Bibliográficos
Autores principales: Zhang, Shehong, Wang, Yuyang, Li, Dake, Wu, Junfa, Si, Wen, Wu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456247/
https://www.ncbi.nlm.nih.gov/pubmed/28930126
http://dx.doi.org/10.3390/medicines3030016