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Necrostatin-1 Attenuates Inflammatory Response and Improves Cognitive Function in Chronic Ischemic Stroke Mice
Multiple cell death is involved in ischemic brain injury. Necroptosis, a recently reported cell death, may be the most suitable cell death mechanism in a subpopulation of neurons under ischemic injury. It reported that a small molecule, necrostatin-1 (Nec-1), has a potent inhibitory effect on necrop...
Autores principales: | Zhang, Shehong, Wang, Yuyang, Li, Dake, Wu, Junfa, Si, Wen, Wu, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456247/ https://www.ncbi.nlm.nih.gov/pubmed/28930126 http://dx.doi.org/10.3390/medicines3030016 |
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