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Linking epigenetic function to electrostatics: The DNMT2 structural model example

The amino acid sequence of DNMT2 is very similar to the catalytic domains of bacterial and eukaryotic proteins. However, there is great variability in the region of recognition of the target sequence. While bacterial DNMT2 acts as a DNA methyltransferase, previous studies have indicated low DNA meth...

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Detalles Bibliográficos
Autores principales: Vieira, Gilberto Cavalheiro, Vieira, Gustavo Fioravanti, Sinigaglia, Marialva, da Silva Valente, Vera Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456315/
https://www.ncbi.nlm.nih.gov/pubmed/28575027
http://dx.doi.org/10.1371/journal.pone.0178643