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Evaluation of macrocyclic hydroxyisophthalamide ligands as chelators for zirconium-89

The development of bifunctional chelators (BFCs) for zirconium-89 immuno-PET applications is an area of active research. Herein we report the synthesis and evaluation of octadentate hydroxyisophthalamide ligands (1 and 2) as zirconium-89 chelators. While both radiometal complexes could be prepared q...

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Detalles Bibliográficos
Autores principales: Bhatt, Nikunj B., Pandya, Darpan N., Xu, Jide, Tatum, David, Magda, Darren, Wadas, Thaddeus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456358/
https://www.ncbi.nlm.nih.gov/pubmed/28575044
http://dx.doi.org/10.1371/journal.pone.0178767