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Pharmacokinetics of caspofungin acetate to guide optimal dosing in cats

Cats are the most common mammal to develop invasive fungal rhinosinusitis caused by cryptic species in Aspergillus section Fumigati that are resistant to azoles but susceptible to caspofungin. In this study nonlinear mixed-effects pharmacokinetic modeling and simulation was used to investigate caspo...

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Detalles Bibliográficos
Autores principales: Leshinsky, Jana, McLachlan, Andrew, Foster, David J. R., Norris, Ross, Barrs, Vanessa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456383/
https://www.ncbi.nlm.nih.gov/pubmed/28575121
http://dx.doi.org/10.1371/journal.pone.0178783