The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort

The methylation status of O-6-methylguanine-DNA methyltransferase (MGMT) is associated with the prognosis in gliomas and in other cancers. Recent studies showed that rs16906252, an SNP in the MGMT promoter, is associated with promoter methylation and is a predictor of the overall survival time (OST)...

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Detalles Bibliográficos
Autores principales: Wei, Kuo-Chen, Chen, Chia-Yuan, Feng, Li-Ying, Huang, Wei-Tzu, Chen, Chia-Hua, Hsu, Peng-Wei, Wang, Kai, Hood, Leroy E., Chen, Leslie Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456392/
https://www.ncbi.nlm.nih.gov/pubmed/28575062
http://dx.doi.org/10.1371/journal.pone.0178842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456392/
https://www.ncbi.nlm.nih.gov/pubmed/28575062
http://dx.doi.org/10.1371/journal.pone.0178842

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