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The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort
The methylation status of O-6-methylguanine-DNA methyltransferase (MGMT) is associated with the prognosis in gliomas and in other cancers. Recent studies showed that rs16906252, an SNP in the MGMT promoter, is associated with promoter methylation and is a predictor of the overall survival time (OST)...
Autores principales: | Wei, Kuo-Chen, Chen, Chia-Yuan, Feng, Li-Ying, Huang, Wei-Tzu, Chen, Chia-Hua, Hsu, Peng-Wei, Wang, Kai, Hood, Leroy E., Chen, Leslie Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456392/ https://www.ncbi.nlm.nih.gov/pubmed/28575062 http://dx.doi.org/10.1371/journal.pone.0178842 |
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