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Nucleolus association of chromosomal domains is largely maintained in cellular senescence despite massive nuclear reorganisation
Mammalian chromosomes are organized in structural and functional domains of 0.1–10 Mb, which are characterized by high self-association frequencies in the nuclear space and different contact probabilities with nuclear sub-compartments. They exhibit distinct chromatin modification patterns, gene expr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456395/ https://www.ncbi.nlm.nih.gov/pubmed/28575119 http://dx.doi.org/10.1371/journal.pone.0178821 |