Cargando…

Patch Clamp Study of Serotonin-Gated Currents via 5-HT Type 3 Receptors by Using a Novel Approach SHAM for Receptor Channel Scanning

We studied 5-hydroxy tryptamine type 3 (5-HT(3)) receptors transfected in tsA-201 cell line to examine serotonin-induced whole cell currents. Using the site-directed mutagenesis technique, we individually mutated each residue in the membrane-spanning M2 segment to histidine. A high proportion of tsA...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaneez, Fatima-Shad, White, M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545651/
https://www.ncbi.nlm.nih.gov/pubmed/15123883
http://dx.doi.org/10.1155/S1110724304302020