Upregulation of miR-375 level ameliorates morphine analgesic tolerance in mouse dorsal root ganglia by inhibiting the JAK2/STAT3 pathway

Several lines of evidence indicate that microRNAs (miRNAs) modulate tolerance to the analgesic effects of morphine via regulation of pain-related genes, making dysregulation of miRNA levels a clinical target for controlling opioid tolerance. However, the precise mechanisms by which miRNAs regulate o...

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Detalles Bibliográficos
Autores principales: Li, Haiqin, Tao, Rong, Wang, Jing, Xia, Lingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457281/
https://www.ncbi.nlm.nih.gov/pubmed/28603428
http://dx.doi.org/10.2147/JPR.S125264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457281/
https://www.ncbi.nlm.nih.gov/pubmed/28603428
http://dx.doi.org/10.2147/JPR.S125264

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