Fatty Acid Binding Protein FABP4 Mechanistically Links Obesity with Aggressive AML by Enhancing Aberrant DNA Methylation in AML Cells

Obesity is becoming more prevalent worldwide and is a major risk factor for cancer development. Acute myeloid leukemia (AML), the most common acute leukemia in adults, remains a frequently fatal disease. Here, we investigated the molecular mechanisms by which obesity favors AML growth and uncovered...

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Detalles Bibliográficos
Autores principales: Yan, F, Shen, N, Pang, JX, Zhang, YW, Rao, EY, Bode, AM, Al-Kali, A, Zhang, DE, Litzow, MR, Li, B, Liu, SJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457366/
https://www.ncbi.nlm.nih.gov/pubmed/27885273
http://dx.doi.org/10.1038/leu.2016.349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457366/
https://www.ncbi.nlm.nih.gov/pubmed/27885273
http://dx.doi.org/10.1038/leu.2016.349

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