β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers

NQO1 is a FAD-binding protein that can form homodimers and reduce quinones to hydroquinones, and a growing body of evidence currently suggests that NQO1 is dramatically elevated in solid cancers. Here, we demonstrated that NQO1 was elevated in breast cancer and that its expression level was positive...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zhou, Xianchun, Xu, Ming, Piao, Junjie, Zhang, Yuan, Lin, Zhenhua, Chen, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457413/
https://www.ncbi.nlm.nih.gov/pubmed/28578385
http://dx.doi.org/10.1038/s41598-017-02937-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457413/
https://www.ncbi.nlm.nih.gov/pubmed/28578385
http://dx.doi.org/10.1038/s41598-017-02937-0

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