RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling

Interferon regulatory factor 5 (IRF5) is a key transcription factor of innate immunity, which plays an important role in host restriction to viral infection and inflammation. Genome-wide association studies have implied the association of IRF5 with several autoimmune diseases, including systemic lup...

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Detalles Bibliográficos
Autores principales: Fu, Bishi, Zhao, Mengmeng, Wang, Lingyan, Patil, Girish, Smith, Jennifer A., Juncadella, Ignacio J., Zuvela-Jelaska, Ljiljana, Dorf, Martin E., Li, Shitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457443/
https://www.ncbi.nlm.nih.gov/pubmed/28578407
http://dx.doi.org/10.1038/s41598-017-02857-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457443/
https://www.ncbi.nlm.nih.gov/pubmed/28578407
http://dx.doi.org/10.1038/s41598-017-02857-z

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