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RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling
Interferon regulatory factor 5 (IRF5) is a key transcription factor of innate immunity, which plays an important role in host restriction to viral infection and inflammation. Genome-wide association studies have implied the association of IRF5 with several autoimmune diseases, including systemic lup...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457443/ https://www.ncbi.nlm.nih.gov/pubmed/28578407 http://dx.doi.org/10.1038/s41598-017-02857-z |