Telomere length correlates with disease severity and inflammation in sickle cell disease

BACKGROUND: Telomeres, the ends of linear chromosomes, shorten during mitotic cell division and erosion may be aggravated by inflammation or proliferative and oxidative stress. As the bone marrow is under hyperproliferative pressure in sickle cell disease and several tissues are submitted to chronic...

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Detalles Bibliográficos
Autores principales: Colella, Marina Pereira, Santana, Barbara A., Conran, Nicola, Tomazini, Vinicius, Costa, Fernando F., Calado, Rodrigo T., Saad, Sara T. Olalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://www.ncbi.nlm.nih.gov/pubmed/28577651
http://dx.doi.org/10.1016/j.bjhh.2017.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457472/
https://www.ncbi.nlm.nih.gov/pubmed/28577651
http://dx.doi.org/10.1016/j.bjhh.2017.02.007

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