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APC/C(Cdh1) Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity

In mammalian females, germ cells remain arrested as primordial follicles. Resumption of meiosis is heralded by germinal vesicle breakdown, condensation of chromosomes, and their eventual alignment on metaphase plates. At the first meiotic division, anaphase-promoting complex/cyclosome associated wit...

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Detalles Bibliográficos
Autores principales: Rattani, Ahmed, Ballesteros Mejia, Randy, Roberts, Katherine, Roig, Maurici B., Godwin, Jonathan, Hopkins, Michael, Eguren, Manuel, Sanchez-Pulido, Luis, Okaz, Elwy, Ogushi, Sugako, Wolna, Magda, Metson, Jean, Pendás, Alberto M., Malumbres, Marcos, Novák, Béla, Herbert, Mary, Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457479/
https://www.ncbi.nlm.nih.gov/pubmed/28502659
http://dx.doi.org/10.1016/j.cub.2017.04.023