RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

Acute myeloid leukemia (AML) is a heterogeneous disease caused by mutations in transcriptional regulator genes, but how different mutant regulators shape the chromatin landscape is unclear. Here, we compared the transcriptional networks of two types of AML with chromosomal translocations of the RUNX...

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Detalles Bibliográficos
Autores principales: Loke, Justin, Assi, Salam A., Imperato, Maria Rosaria, Ptasinska, Anetta, Cauchy, Pierre, Grabovska, Yura, Soria, Natalia Martinez, Raghavan, Manoj, Delwel, H. Ruud, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457485/
https://www.ncbi.nlm.nih.gov/pubmed/28538183
http://dx.doi.org/10.1016/j.celrep.2017.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457485/
https://www.ncbi.nlm.nih.gov/pubmed/28538183
http://dx.doi.org/10.1016/j.celrep.2017.05.005

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