Cargando…

Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis

Human T-cell leukaemia virus type-1 (HTLV-1) and bovine leukaemia virus (BLV) infect T- and B-lymphocytes, respectively, provoking a polyclonal expansion that will evolve into an aggressive monoclonal leukaemia in ∼5% of individuals following a protracted latency period. It is generally assumed that...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosewick, Nicolas, Durkin, Keith, Artesi, Maria, Marçais, Ambroise, Hahaut, Vincent, Griebel, Philip, Arsic, Natasa, Avettand-Fenoel, Véronique, Burny, Arsène, Charlier, Carole, Hermine, Olivier, Georges, Michel, Van den Broeke, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457497/
https://www.ncbi.nlm.nih.gov/pubmed/28534499
http://dx.doi.org/10.1038/ncomms15264