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Decoding and reprogramming fungal iterative nonribosomal peptide synthetases

Nonribosomal peptide synthetases (NRPSs) assemble a large group of structurally and functionally diverse natural products. While the iterative catalytic mechanism of bacterial NRPSs is known, it remains unclear how fungal NRPSs create products of desired length. Here we show that fungal iterative NR...

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Detalles Bibliográficos
Autores principales: Yu, Dayu, Xu, Fuchao, Zhang, Shuwei, Zhan, Jixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457498/
https://www.ncbi.nlm.nih.gov/pubmed/28534477
http://dx.doi.org/10.1038/ncomms15349