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Decoding and reprogramming fungal iterative nonribosomal peptide synthetases
Nonribosomal peptide synthetases (NRPSs) assemble a large group of structurally and functionally diverse natural products. While the iterative catalytic mechanism of bacterial NRPSs is known, it remains unclear how fungal NRPSs create products of desired length. Here we show that fungal iterative NR...
Autores principales: | Yu, Dayu, Xu, Fuchao, Zhang, Shuwei, Zhan, Jixun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457498/ https://www.ncbi.nlm.nih.gov/pubmed/28534477 http://dx.doi.org/10.1038/ncomms15349 |
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