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Molecular basis for PrimPol recruitment to replication forks by RPA

DNA damage and secondary structures can stall the replication machinery. Cells possess numerous tolerance mechanisms to complete genome duplication in the presence of such impediments. In addition to translesion synthesis (TLS) polymerases, most eukaryotic cells contain a multifunctional replicative...

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Detalles Bibliográficos
Autores principales: Guilliam, Thomas A., Brissett, Nigel C., Ehlinger, Aaron, Keen, Benjamin A., Kolesar, Peter, Taylor, Elaine M., Bailey, Laura J., Lindsay, Howard D., Chazin, Walter J., Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457501/
https://www.ncbi.nlm.nih.gov/pubmed/28534480
http://dx.doi.org/10.1038/ncomms15222