11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from intrinsically inert metabolites. The present study aim...

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Detalles Bibliográficos
Autores principales: Mylonas, Katie J, Turner, Neil A, Bageghni, Sumia A, Kenyon, Christopher J, White, Christopher I, McGregor, Kieran, Kimmitt, Robert A, Sulston, Richard, Kelly, Valerie, Walker, Brian R, Porter, Karen E, Chapman, Karen E, Gray, Gillian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457506/
https://www.ncbi.nlm.nih.gov/pubmed/28522730
http://dx.doi.org/10.1530/JOE-16-0501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457506/
https://www.ncbi.nlm.nih.gov/pubmed/28522730
http://dx.doi.org/10.1530/JOE-16-0501

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