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11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI
We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from intrinsically inert metabolites. The present study aim...
Autores principales: | Mylonas, Katie J, Turner, Neil A, Bageghni, Sumia A, Kenyon, Christopher J, White, Christopher I, McGregor, Kieran, Kimmitt, Robert A, Sulston, Richard, Kelly, Valerie, Walker, Brian R, Porter, Karen E, Chapman, Karen E, Gray, Gillian A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457506/ https://www.ncbi.nlm.nih.gov/pubmed/28522730 http://dx.doi.org/10.1530/JOE-16-0501 |
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