Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1

Physical exercise can improve brain function and delay neurodegeneration; however, the initial signal from muscle to brain is unknown. Here we show that the lactate receptor (HCAR1) is highly enriched in pial fibroblast-like cells that line the vessels supplying blood to the brain, and in pericyte-l...

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Detalles Bibliográficos
Autores principales: Morland, Cecilie, Andersson, Krister A., Haugen, Øyvind P., Hadzic, Alena, Kleppa, Liv, Gille, Andreas, Rinholm, Johanne E., Palibrk, Vuk, Diget, Elisabeth H., Kennedy, Lauritz H., Stølen, Tomas, Hennestad, Eivind, Moldestad, Olve, Cai, Yiqing, Puchades, Maja, Offermanns, Stefan, Vervaeke, Koen, Bjørås, Magnar, Wisløff, Ulrik, Storm-Mathisen, Jon, Bergersen, Linda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457513/
https://www.ncbi.nlm.nih.gov/pubmed/28534495
http://dx.doi.org/10.1038/ncomms15557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457513/
https://www.ncbi.nlm.nih.gov/pubmed/28534495
http://dx.doi.org/10.1038/ncomms15557

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