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Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
Physical exercise can improve brain function and delay neurodegeneration; however, the initial signal from muscle to brain is unknown. Here we show that the lactate receptor (HCAR1) is highly enriched in pial fibroblast-like cells that line the vessels supplying blood to the brain, and in pericyte-l...
Autores principales: | Morland, Cecilie, Andersson, Krister A., Haugen, Øyvind P., Hadzic, Alena, Kleppa, Liv, Gille, Andreas, Rinholm, Johanne E., Palibrk, Vuk, Diget, Elisabeth H., Kennedy, Lauritz H., Stølen, Tomas, Hennestad, Eivind, Moldestad, Olve, Cai, Yiqing, Puchades, Maja, Offermanns, Stefan, Vervaeke, Koen, Bjørås, Magnar, Wisløff, Ulrik, Storm-Mathisen, Jon, Bergersen, Linda H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457513/ https://www.ncbi.nlm.nih.gov/pubmed/28534495 http://dx.doi.org/10.1038/ncomms15557 |
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