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Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads
BACKGROUND: Protein ubiquitylation is an important post-translational regulation, which has been shown to be necessary for life cycle progression and survival of Plasmodium falciparum. Ubiquitin is a highly conserved 76 amino acid polypeptide, which attaches covalently to target proteins through com...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457628/ https://www.ncbi.nlm.nih.gov/pubmed/28577368 http://dx.doi.org/10.1186/s40360-017-0147-4 |