Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice

Several members of the Bcl-2 gene family are dysregulated in human temporal lobe epilepsy and animal studies show that genetic deletion of some of these proteins influence electrographic seizure responses to chemoconvulsants and associated brain damage. The BH3-only proteins form a subgroup comprisi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichikawa, Naoki, Alves, Mariana, Pfeiffer, Shona, Langa, Elena, Hernández-Santana, Yasmina E, Suzuki, Hidenori, Prehn, Jochen HM, Engel, Tobias, Henshall, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457684/
https://www.ncbi.nlm.nih.gov/pubmed/28079889
http://dx.doi.org/10.1038/cddis.2016.301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457684/
https://www.ncbi.nlm.nih.gov/pubmed/28079889
http://dx.doi.org/10.1038/cddis.2016.301

Ejemplares similares