Cargando…

Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice

Several members of the Bcl-2 gene family are dysregulated in human temporal lobe epilepsy and animal studies show that genetic deletion of some of these proteins influence electrographic seizure responses to chemoconvulsants and associated brain damage. The BH3-only proteins form a subgroup comprisi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ichikawa, Naoki, Alves, Mariana, Pfeiffer, Shona, Langa, Elena, Hernández-Santana, Yasmina E, Suzuki, Hidenori, Prehn, Jochen HM, Engel, Tobias, Henshall, David C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457684/ https://www.ncbi.nlm.nih.gov/pubmed/28079889 http://dx.doi.org/10.1038/cddis.2016.301

Ejemplares similares

Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus
por: Engel, T, et al.
Publicado: (2010)

BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis
por: Wensveen, Felix M., et al.
Publicado: (2013)

BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
por: Roufayel, Rabih, et al.
Publicado: (2022)

Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury
por: Pfeiffer, S, et al.
Publicado: (2014)

The Impact of Electrographic Seizures on Developing Hippocampal Dendrites Is Calcineurin Dependent
por: Nishimura, Masataka, et al.
Publicado: (2017)

BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis
por: Holzerland, Julia, et al.
Publicado: (2020)

Three Cases of Aphasic Status Epilepticus: Clinical and Electrographic Characteristics
por: Lee, Jung-Ju, et al.
Publicado: (2021)

Electrographic Features of Spontaneous Recurrent Seizures in a Mouse Model of Extended Hippocampal Kindling
por: Liu, Haiyu, et al.
Publicado: (2021)

BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus
por: Bunk, E C, et al.
Publicado: (2010)

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa
por: Naik, Edwina, et al.
Publicado: (2007)

Incidence of Electrographic Seizures in Patients With COVID-19
por: Waters, Brandon L., et al.
Publicado: (2021)

The role of BH3-only protein Bmf in the pathogenesis of dominant negative hepatocyte nuclear factor-1 –induced mature-onset diabetes of the young in transgenic mice
por: Alkhalifah, Fahd, et al.
Publicado: (2015)

Short-Term Effects of Phenobarbitone on Electrographic Seizures in Neonates
por: Low, Evonne, et al.
Publicado: (2016)

Electrographic Seizures in Neonates with a High Risk of Encephalopathy
por: Chen, Wan-Hsuan, et al.
Publicado: (2022)

BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death Induced by Hypoxia-inducible Factor 1α
por: Kim, Jee-Youn, et al.
Publicado: (2004)

The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents
por: Karbon, Gerlinde, et al.
Publicado: (2021)

Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury
por: Engel, Tobias, et al.
Publicado: (2017)

BH3-Only protein bmf is required for the maintenance of glucose homeostasis in an in vivo model of HNF1α-MODY diabetes
por: Pfeiffer, S, et al.
Publicado: (2015)

Electrographic Changes Accompanying Recurrent Seizures under Ketogenic Diet Treatment
por: Lucchi, Chiara, et al.
Publicado: (2017)

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus
por: Batool, Aasia, et al.
Publicado: (2020)

Gefitinib Analogue V1801 Induces Apoptosis of T790M EGFR-Harboring Lung Cancer Cells by Up-Regulation of the BH-3 Only Protein Noxa
por: Zhang, Bo, et al.
Publicado: (2012)

Electrographic seizures after subarachnoid hemorrhage lead to derangement of brain homeostasis in humans
por: Claassen, J, et al.
Publicado: (2011)

Early Electrographic Seizures, Brain Injury an Neurodevelopmental Risk in the Very Preterm Infant
por: Vesoulis, Zachary A., et al.
Publicado: (2013)

Dynamic causal modelling of electrographic seizure activity using Bayesian belief updating
por: Cooray, Gerald K., et al.
Publicado: (2016)

Diagnostic accuracy between readers for identifying electrographic seizures in critically ill adults
por: Tu, Bin, et al.
Publicado: (2017)

Electrographic seizure monitoring with a novel, wireless, single-channel EEG sensor
por: Frankel, Mitchell A., et al.
Publicado: (2021)

Electrographic seizures and brain hyperoxia may be key etiological factors for postconcussive deficits
por: Malik, Haris, et al.
Publicado: (2022)

A Commentary on Electrographic Seizure Management and Clinical Outcomes in Critically Ill Children
por: Tran, Lily, et al.
Publicado: (2023)

Epileptiform Discharge and Electrographic Seizures during the Hypothermia Phase as Predictors of Rewarming Seizures in Children after Resuscitation
por: Lin, Jainn-Jim, et al.
Publicado: (2020)

Gene expression during ER stress–induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
por: Reimertz, Claus, et al.
Publicado: (2003)

Evidence for spreading seizure as a cause of theta-alpha activity electrographic pattern in stereo-EEG seizure recordings
por: Sip, Viktor, et al.
Publicado: (2021)

Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs
por: Afrikanova, Tatiana, et al.
Publicado: (2013)

Machine learning for the early prediction of infants with electrographic seizures in neonatal hypoxic‐ischemic encephalopathy
por: Pavel, Andreea M., et al.
Publicado: (2022)

AT101 [(-)-Gossypol] Selectively Inhibits MCL1 and Sensitizes Carcinoma to BH3 Mimetics by Inducing and Stabilizing NOXA
por: Mallick, David J., et al.
Publicado: (2020)

AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis
por: Concannon, Caoimhín G., et al.
Publicado: (2010)

Suppression of Electrographic Seizures Is Associated with Amelioration of QTc Interval Prolongation in Patients with Traumatic Brain Injury
por: Dabrowski, Wojciech, et al.
Publicado: (2021)

The role of spreading depolarizations and electrographic seizures in early injury progression of the rat photothrombosis stroke model
por: Schoknecht, Karl, et al.
Publicado: (2020)

VEEG monitoring and electrographic seizures in 232 pediatric patients in ICU at a tertiary hospital in China
por: Sang, Tian, et al.
Publicado: (2022)

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA
por: Subramanian, Aishwarya, et al.
Publicado: (2016)

Effect of Treatment of Clinical Seizures vs Electrographic Seizures in Full-Term and Near-Term Neonates: A Randomized Clinical Trial
por: Hunt, Rod W., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l9ompeobea8ogdcr3u7888g8s6