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How biologically relevant are interaction-based modules in protein networks?

By applying a graph-based algorithm to yeast protein-interaction networks we have extracted modular structures and show that they can be validated using information from the phylogenetic conservation of the network components. We show that the module cores, the parts with the highest intramodular co...

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Detalles Bibliográficos
Autores principales: Poyatos, Juan F, Hurst, Laurence D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545784/
https://www.ncbi.nlm.nih.gov/pubmed/15535869
http://dx.doi.org/10.1186/gb-2004-5-11-r93