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Integrating phenotypic and expression profiles to map arsenic-response networks

BACKGROUND: Arsenic is a nonmutagenic carcinogen affecting millions of people. The cellular impact of this metalloid in Saccharomyces cerevisiae was determined by profiling global gene expression and sensitivity phenotypes. These data were then mapped to a metabolic network composed of all known bio...

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Detalles Bibliográficos
Autores principales: Haugen, Astrid C, Kelley, Ryan, Collins, Jennifer B, Tucker, Charles J, Deng, Changchun, Afshari, Cynthia A, Brown, J Martin, Ideker, Trey, Van Houten, Bennett
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545798/
https://www.ncbi.nlm.nih.gov/pubmed/15575969
http://dx.doi.org/10.1186/gb-2004-5-12-r95